Comparison of Dopamine and Norepinephrine in the Treatment of Shock

Comparison of Dopamine and Norepinephrine in the Treatment of Shock

N Engl J Med 2010;362:779-89.

 

Both dopamine and norepinephrine are recommended as first-line vasopressor agent
in the treatment of shock. There is a continuing controversy about whether one agent
is superior to the other.In this multicenter, randomized trial, we assigned patients with shock to receive either dopamine or norepinephrine as first-line vasopressor therapy to restore and maintain blood pressure.
 
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